The Stupp Laboratory
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research news Stupp Group 2014


Northwestern University


Ronald Breslow Award for Achievement in Biomimetic Chemistry

Chemical & Engineering News
by Britt E. Erickson
January 21, 2013

A leader in supramolecular self-assembly, Samuel I. Stupp is being honored for his work on developing bioactive materials that could revolutionize therapies in regenerative medicine. Stupp is well-known for creating an extensive platform of self-assembling molecules, especially those based on peptide amphiphiles that form nanofibers, resulting in broadly bioactive synthetic materials......more

New Geometries: Researchers Create New Shapes of Artificial Microcompartments

Northwestern University, McCormick News
by Sarah Ostman
December 11, 2012

In nature, biological functions are often carried out in tiny protective shells known as microcompartments, structures that provide home to enzymes that convert carbon dioxide into energy in plant cells and to viruses that replicate once they enter the cell.......more

New Computer Memory Material Goes Easy on the Juice

Science Magazine, News
by Robert F. Service
August 24, 2012

Multitasking has a price: Your computer is sucking up a lot of electricity keeping track of work you haven't yet saved to the hard drive. Americans spend $6 billion a year on electricity to keep that data stored in a computer's memory during operation. But that figure could drop sharply, scientists report this week, thanks to a new type of material than can permanently store such data—without needing a continuous trickle of electricity to do it.......more

Toward Better Ferroelectrics

Chemical & Engineering News,Science & Technology
by Lauren K. Wolf
August 23, 2012

New organic ferroelectric materials that operate at room temperature made their debut at the American Chemical Society national meeting in Philadelphia this week. Scientists have in the past synthesized ferroelectrics of this type—mixed stacks of electron-donating and electron-accepting small molecules. But the materials had only been able to function at cryogenic temperatures, which are impractical for real-world use.

Ferroelectrics, found in ultrasound imaging equipment and computer memory, are prized for their ability to flip polarization when exposed to an external electric field. Because the materials are currently made of inorganic compounds such as barium titanate, researchers have been seeking alternatives that are cheaper, lighter, and easier to fabricate.......more

Room-Temperature Ferroelectricity in Supramolecular Networks of Charge-Transfer Complexes

Courtesy of Nature

Nature 488(7412), (2012) 485-489.

A. S. Tayi
A. K. Shveyd
C-H. Sue
J. M. Szarko
B. S. Rolczynski
D. Cao
T. J. Kennedy
A. A. Sarjeant
C. L. Stern
W. F. Paxton
W. Wu
S. K. Dey
A. C. Fahrenbach
J. R. Guest
H. Mohseni
L. X. Chen
K. L. Wang
J. F. Stoddart
S. I. Stupp

“Functional Supramolecular Polymers”

Cover Image Courtesy of Science Mag

Science 335(6070), (2012) 813-817.

T. Aida
E. W. Meijer
S. I. Stupp

“Supramolecular Nanostructures that Mimic VEGF as a strategy for Ischemic Tissue Repair”

Courtesy of PNAS

Proc. Natl. Acad. Sci. 108(33), (2011) 13438-13443.

M. J. Webber
J. Tongers
C. J. Newcomb
K-T. Marquardt
J. Bauersachs
D. W. Losordo
S. I. Stupp



Regular Group Meetings

08/05/14 Tuesday @ 4:00pm - Baldwin (Lurie)- Special Group Meeting

08/07/14 Thursday @ 4:00pm - Cook 2058- Summer Students

08/28/14 Thursday @ 4:00pm - Cook 2058- Charles Rubert and Zhilin Yu

09/02/14 Tuesday @ 4:00pm - Searle- Nicholas Sather and Miranda So

09/08/14 Monday @ 4:00pm - Gray - Benjamin Jones and Stacey Chin

09/11/14 Thursday @ 4:00pm - Cook 2058- Christopher Serrano and Ashwin Narayanan

09/15/14 Monday @ 4:00pm - Cook 2058- Garrett Lau and Charlotte Chen



Weekly Subgroup Meetings

Subgroup 1 - Solar (Photovoltaics):
Wednesdays, 4:00 p.m., Cook 3024
Contact: Adam Weingarten

Subgroup 2 - Self-Assembly:
Tuesdays, 11:00 a.m., Cook 3024
Contact: Mark McClendon

Subgroup 3 - Biomaterials:
Thursdays, 9:00 a.m., IBNAM Conference Rm, Chicago campus, Lurie Bldg. 11th Fl

Contact: Charles Rubert


The Stupp Group 2014

Stupp Group 2014

The Stupp Laboratory
Cook Hall 1127
2220 Campus Drive
Evanston, IL 60208-3108

(847) 491-3002 phone
(847) 491-3010 facsimile

Samuel I. Stupp
Board of Trustees Professor of
Materials Science, Chemistry, & Medicine
Director, Institute for BioNanotechnology in Medicine
Director, Simpson Querrey Insitute for BioNanotechnology in Medicine


Sharon Jacknow
Research Administrator

Jill Johnson
Program Manager
Chicago Campus

Laura Fields
Assistant to Professor Stupp
Evanston Campus

Kyle Johnson
Administrative Assistant
Chicago Campus

Recently Published

β1-integrin and Integrin Linked Kinase Regulate Astrocytic Differentiation of Neural Stem Cells
Pan, L.; North, H. A.; Sahni, V.; Jeong, S. J.; McGuire, T. L.; Berns, E.; Stupp, S. I.; Kessler, J. A. PLOS One 2014, In Press. DOI: 10.1371/journal.pone.0104335 

“Enhanced Potency of Cell-Based Therapy for Ischemic Tissue Repair using an Injectable Bioactive Epitope-Presenting Nanofiber Support Matrix
Tongers, J.; Webber, M. J.; Vaughn, E. E.; Sleep, E.; Renault, M-A.; Roncalli, J. G.; Klyachko, E.; Thorne, T.; Yu, Y.; Marquardt, K-T.; Kamide, C. E.; Ito, A.; Misener, S.; Millay, M.; Liu, T.; Jujo, K.; Qin, G.; Losordo, D. W.; Stupp, S. I.; Kishore, R.; J. Mol. Cell. Cardiol. 74 (2014) 231-239. 

“A Bioengineered Peripheral Nerve Construct Using Aligned Peptide Amphiphile Nanofibers
Li, A.; Hokugo, A.; Yalom, A.; Berns, E. J.; Stephanopoulos, N.; McClendon, M. T.; Segovia, L. A.; Spigelman, I.; Stupp, S. I.; Jarrahy, R. Biomaterials (2014), In Press. DOI: 10.1016/jbiomaterials.2014.06.049

Gd(III)-Labeled Peptide Nanofibers for Reporting on Biomaterial Localization In Vivo 
Preslar, A. T.; Parigi, G.; McCLendon, M. T.; Sefick, S. S.; Moyer, T. J.; Haney, C. R.; Waters, E. A.; MacRenaris, K. W.; Luchinat, C.; Stupp, S. I.; Meade, T. J. ACS Nano 8(7), (2014) 7325-7332.

Pathway Selection in Peptide Amphiphile Assembly
Korevaar, P. A.; Newcomb, C. J.; Meijer, E. W.; Stupp, S. I. J. Am. Chem. Soc. 136(24), (2014) 8540-8543.

“Internal Dynamics of a Supramolecular Nanofiber”
Ortony, J. H.; Newcomb, C.; Matson, J. B.; Palmer, L. C.; Doan, P. E.; Hoffman, B. M.; Stupp, S. I. Nature Materials 13, (2014) 812-816.

Gel Scaffolds of BMP-2-binding Peptide Amphiphile Nanofibers for Spinal Arthrodesis
Lee, S. S.; Hsu, E. L.; Mendoza, M.; Ghodasra, J.; Nickoli, M. S.; Ashtekar, A.; Polavarapu, M.; Babu, J.; Riaz, R. M.; Nicolas, J. D.; Nelson, D.; Hashmi, S. Z.; Earhart, J. S.; Merk, B. R.; McKee, J. S.; Bairstow, S. F.; Shah, R. N.; Hsu, W. K.; Stupp, S. I. Advanced Healthcare Materials (2014), In Press. DOI: 10.1002/adhm.201400129 

Electrospinning Bioactive Supramolecular Polymers From Water”
Tayi, T. S.; Pashuck, E. T.; Newcomb, C. J.; McClendon, M. T.; Stupp, S. I. Biomacromolecules, 15(4), (2014) 1323-1327. 

Post-Assembly Functionalization of Supramolecular Nanostructures with Bioactive Peptides and Fluorescent Proteins by Native Chemical Ligation"
Khan, S,; Sur, S.; Dankers, P.Y.W.; da Silva, R. M. P.; Boekhoven, J.; Poor, T. A.; Stupp, S. I. Bioconjugate Chemistry 25(4), (2014) 707-717.

Redox Switchable Daisy Chain Rotaxanes Driven by Radical-Radical Interactions
Bruns, C. J.; Frasconi, M.; Iehl, J.; Hertlieb, K. J.; Schneebeli, S. T.; Cheng, C.; Stupp, S. I.; Stoddart, J. F.; J. Am. Chem. Soc. 136(12), (2014) 4714-4723.




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Northwestern University
Robert R. McCormick School of Engineering & Applied Science | Department of Materials Science & Engineering
Judd A. and Marjorie Weinberg College of Arts and Sciences | Department of Chemistry
Feinberg School of Medicine | Institute for BioNanotechnology in Medicine
The Stupp Laboratory | Cook Hall 1127 | 2220 Campus Drive | Evanston, IL 60208 | U.S.A.
Phone: 847-491-3002 Fax: 847-491-3010
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